UFC Fight Night 166: Blaydes vs. dos Santos was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on January 25, 2020 at PNC Arena in Raleigh, North Carolina, United States. A heavyweight bout between Curtis Blaydes and former UFC Heavyweight Champion Junior dos Santos served as the event headliner.

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Main Cast: Curtis Blaydes, Junior dos Santos, Michael Chiesa, Rafael dos Anjos, Alex Perez, Jordan Espinosa, Angela Hill, Hannah Cifers, Jamahal Hill, Darko Stošić

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