ONE Championship: Titles and Titans (also known as ONE Championship 45) was a mixed martial arts event held by ONE Championship. The event was held on August 27, 2016 at the Jakarta Convention Center in Jakarta, Indonesia.

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Main Cast: Sami Amin, Saygid Arslanaliev, Jake Butler, Anthony Engelen, Jietebusibai Haolan, Yohan Mulia Legowo, Sunoto Peringkat, Marcin Prachnio, Luis Santos, Islam Sayed

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