The PFL 4 mixed martial arts event for the 2022 season of the Professional Fighters League was held on June 17, 2022 at the Overtime Elite Arena in Atlanta, Georgia. This marked the fourth regular season event of the tournament and included fights in the Lightweight and Light Heavyweight divisions.

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Main Cast: Alexander Martinez, Clay Collard, Antônio Carlos Júnior, Bruce Souto, Olivier Aubin-Mercier, Raush Manfio, Jeremy Stephens, Myles Price, Omari Akhmedov, Teodoras Aukštuolis

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