The PFL 2 mixed martial arts event for the 2018 season of the Professional Fighters League was held on June 21, 2018, at the Chicago Theatre in Chicago, Illinois. It was the second regular season event of 2018 and included only fights in the lightweight and light heavyweight divisions.

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Main Cast: Will Brooks, Luiz Firmino, Brian Foster, Ramsey Nijem, Kayla Harrison, Brittney Elkin, Efrain Escudero, Jason High, Sean O'Connell, Ronny Markes

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